The evolutionarily conserved RNA helicase DDX6 is a central player in post-transcriptional regulation. but its role during embryogenesis remains elusive. We here show that DDX6 enables proper cell lineage specification from pluripotent cells by analyzing Ddx6 knockout (KO) mouse embryos and employing an in vitro epiblast-like cell (EpiLC) induction system. Our study unveils that DDX6 ... https://www.tourettebrewing.com/