Not all patients with CLL have to have therapy. In spite of all the latest advancements, the iwCLL nonetheless endorses watchful observation for sufferers with asymptomatic disease.86 This suggestion is based on at least two randomized trials evaluating observation to possibly chlorambucil monotherapy or fludarabine, cyclophosphamide and rituximab (FCR). Dari https://juliaw975vel2.dekaronwiki.com/user